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Acute sensorineural deafness in Lassa fever

This resource describes a prospective audiometric evaluation of 69 hospitalized febrile patients in Sierra Leone, West Africa, that revealed a sensorineural hearing deficit (SNHD) in 14 (29%) of 49 confirmed cases of Lassa fever and in 0 of 20 febrile controls. This study found that lassa fever is associated with an incidence of SNHD, which considerably exceeds that previously reported with any other postnatally acquired infection.

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Nigeria Centre for Disease Control (NCDC): Standard operating procedures for Lassa fever case management

This resource describes the standard operating procedures for Lassa fever case management as outlined by the Nigeria Centre for Disease Control.

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Sensorineural hearing loss in Lassa fever: Two case reports

This resource reports on two female patients aged 19 and 43 years old with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction. Both patients developed severe sensorineural hearing loss at acute phases of the infections.

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World Health Organisation: Lassa fever in Sierra Leone

This is an update on Lassa fever in Sierra Leone from the 14th June 1996. 

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The process and practice of diagnosis: Innovations in diagnostics for Lassa fever in Sierra Leone

Chapter 5 of Annie Wilkinson’s PhD thesis, provides a detailed description of health seeking behaviours for Lassa Fever in rural Sierra Leone. In this context, people interpreted and managed Lassa Fever in light of their familiarity with a wide range of other diseases, some of which were viewed as dangerous and others less so; in contexts where sickness, health and treatment were marked by uncertainty; and where hospitals were not necessarily perceived to be sites of good care.  An important insight is that people differentiated ‘big sick’ or ‘hospital sick’ from an ordinary or ‘small’ sick and it was partly on the basis of this distinction that people would choose to access care.

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Healthcare providers on the frontlines: A qualitative investigation of the social and emotional impact of delivering health services during Sierra Leone’s Ebola epidemic

This paper describes the stigma experienced by health care workers during the Ebola epidemic in Sierra Leone, and recommends psychological support mechanisms for medical staff working in epidemic contexts.

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Perceptions of burden of caregiving by informal caregivers of cancer patients attending University of Calabar Teaching Hospital, Calabar, Nigeria

Though not about Lassa fever specifically, this study shows the burden experienced by informal caregivers of cancer patients in Nigeria. Most caregivers experienced this burden as moderate or severe.

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Patients’ and healthcare providers’ perceptions and practices regarding hypertension, pharmacy-based care, and mHealth in Lagos, Nigeria

Although not focused on Lassa Fever, a recent publication on hypertension in Nigeria, provides a comprehensive review of contemporary health seeking behaviour in the country, underlining the important role that small-scale local pharmaceutical providers provide as the front line of medical care.  This study also describes what respondents call a ‘Nigerian Factor’; a reluctance to seek health care until very sick.

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Safe intensive-care management of a severe case of Lassa fever with simple barrier nursing techniques

This resource describes the case-management of Lassa fever in a specific patient and the difficulties encountered in repatriating her for diagnosis and management, which is unavailable in Sierra Leone, are described.The experience with this case has implications for the medical care and safe handling of Lassa fever in both endemic and nonendemic areas.

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Lassa fever: Epidemiology, clinical features, and social consequences

This resource describes the epidemiology of Lassa fever and its vector, as well as the clinical course and management of the disease. It then reports on current treatment efforts, surveillance and disease control before presenting community perspectives through a knowledge, attitude and practice survey and a qualitative study.  

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