Resources

Power, fairness and trust : understanding and engaging with vaccine trial participants and communities in the setting up the EVOVAC-Salone vaccine trial in Sierra Leone

In this article the authors discuss the implementation of an Ebola vaccine trial in Kambia district in Sierra Leone during and after the epidemic. They analyze the role of social science research for the development of community engagement strategies. The authors give special attention to the analysis of rumours as source of information and explanation about resistance rooted in a much deeper sociopolitical context.

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Safe intensive-care management of a severe case of Lassa fever with simple barrier nursing techniques

This resource describes the case-management of Lassa fever in a specific patient and the difficulties encountered in repatriating her for diagnosis and management, which is unavailable in Sierra Leone, are described.The experience with this case has implications for the medical care and safe handling of Lassa fever in both endemic and nonendemic areas.

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EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country

This article describes the experiences of the EBOVAC-Salone research team in setting up and implementing the trial, and provides recommendations for research teams aiming to conduct clinical trials in future outbreak situations.

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Lassa fever: Epidemiology, clinical features, and social consequences

This resource describes the epidemiology of Lassa fever and its vector, as well as the clinical course and management of the disease. It then reports on current treatment efforts, surveillance and disease control before presenting community perspectives through a knowledge, attitude and practice survey and a qualitative study.  

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WHO: 1996 - Lassa fever in Sierra Leone - update 2

The conclusion of the WHO support mission is that a major epidemic of Lassa Fever has occurred in Kailahun and Kenema Districts and is continuing as unusually large numbers of severely ill patients are still being admitted to hospital, with a large number of deaths still occurring.

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Emerging disease or emerging diagnosis?: Lassa fever and Ebola in Sierra Leone

This article looks beyond Ebola in 2014 to the history of efforts to control VHFs in the Mano River and challenges the idea that there was a vacuum of knowledge. Highlighted instead are politics of knowledge which have run through global health and which have prioritized particular forms of knowledge and ways of dealing with disease. Ethnographic research on the emergence of Lassa and the subsequent emergence of Ebola in West Africa is presented, focusing on the development of technologies and institutions to detect and manage both viruses.

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Lassa fever

In a study of Lassa fever in Sierra Leone, West Africa, this paper identifies two variables associated with a high risk of death, and evaluates the efficacy of ribavirin and Lassa virus–convalescent plasma for the treatment of Lassa fever.

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