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Displaying 1 - 10 of 14 results.

WHO: Lassa fever research and development (R&D) roadmap

This resource provides a framework for identifying the vision, underpinning strategic goals, and prioritizing areas and activities for accelerating the collaborative development of medical countermeasures.

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Power, fairness and trust : understanding and engaging with vaccine trial participants and communities in the setting up the EVOVAC-Salone vaccine trial in Sierra Leone

In this article the authors discuss the implementation of an Ebola vaccine trial in Kambia district in Sierra Leone during and after the epidemic. They analyze the role of social science research for the development of community engagement strategies. The authors give special attention to the analysis of rumours as source of information and explanation about resistance rooted in a much deeper sociopolitical context.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

This resource describes the main challenges of the implementation of a trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, it reports the aspects of the community’s communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved.

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U.S. Centre for Disease Control (CDC): Lassa fever

Further information from the U.S. CDC in both English and French about the transmission, prevention, diagnosis and treatment of Lassa fever.

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U.S Centre for Disease Control (CDC): Ebola hemorrhagic fever information packet

This resource provides a fact sheet for Ebola as well as a case count and location list for April 9th, 2010.

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Safe intensive-care management of a severe case of Lassa fever with simple barrier nursing techniques

This resource describes the case-management of Lassa fever in a specific patient and the difficulties encountered in repatriating her for diagnosis and management, which is unavailable in Sierra Leone, are described.The experience with this case has implications for the medical care and safe handling of Lassa fever in both endemic and nonendemic areas.

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Popular concerns about medical research projects in sub-Saharan Africa – a critical voice in debates about medical research ethics

This resource aims to move beyond the dismissal of stories about blood-stealing and trade in body parts as ‘mere’ rumour, based on erroneous belief or traditional superstition, and to instead appreciate them as modern commentaries on social relations that involve, and extend far beyond, scientific medical research.

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EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country

This article describes the experiences of the EBOVAC-Salone research team in setting up and implementing the trial, and provides recommendations for research teams aiming to conduct clinical trials in future outbreak situations.

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Ethics and the ethnography of medical research in Africa

This resource outlines two emerging approaches to medical ethics, and summarises each of seven papers selected from the conference for inclusion in this special issue on ethics and ethnography, and finally highlights two areas of lively debate at the conference itself: the appropriateness and value of ethics guidelines and review boards for medical research; and the ethical review of social science research.

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Lassa fever: Epidemiology, clinical features, and social consequences

This resource describes the epidemiology of Lassa fever and its vector, as well as the clinical course and management of the disease. It then reports on current treatment efforts, surveillance and disease control before presenting community perspectives through a knowledge, attitude and practice survey and a qualitative study.  

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