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Ebola hemorrhagic fever outbreaks in Gabon 1994-1997

This resource describes the fall 1994 epidemic in Gabon and a retrospective check for other etiologic agents due atypical aspects of Yellow fever infection during the epidemic. The paper then highlights the beneficial use of barrier nursing techniques in limiting disease spread and in the prevention of future Ebola hemorrhagic fever epidemics.

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Lassa fever. Epidemiological aspects of the 1970 epidemic

This resource describes the contact tracing of patients during a hospital centred outbreak of Lassa fever in early 1970 in Jos, Nigeria. 

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Sierra Leone continues to struggle for relief from Lassa fever

This short article in The Lancet describes the issues faced by the medical relief charity MERLIN, which provides Lassa fever services in Sierra Leone, during and after the civil war. 

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Mystery virus from Lassa

Two sisters, both with a deep and abiding religious faith, tell the story of their involvement with a severe but unknown viral disease. One is a missionary nurse. Lily, who caught the disease; the other is Rose, who cared for her when she was brought back to the States. The shared story began with a letter from Lily.

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Understanding the cryptic nature of Lassa fever in West Africa

This resource synthesizes current knowledge of Lassa fever (LF) recoligy, epidemiology and distribution to show that extrapolations from past research have produced an incomplete picture of the incidence and distribution of LF, with negative consequences for policy planning, medical treatment and management interventions.

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Epidemics of Ebola haemorrhagic fever in Gabon (1994-2002)

This resource considers the cultural and psycho-sociological aspects accounting for the difficulty to implement control measures during the Ebola haemorrhagic fever epidemics in Gabon between 1994 and 2002. It discusses the possibilities of better surveillance and a quick management of intervention means, including a regional permanent pre-alert.

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Organizing the donation of convalescent plasma for a therapeutic clinical trial on Ebola Virus Disease: The experience in Guinea

This resource reports on the successful organization of donor mobilization and plasma collection as part of the Ebola-Tx clinical trial from November 2014 to July 2015 in Conakry, Guinea, the challenges they faced, and efforts made to address these.

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Impact of Lassa fever on the practice and consumption of stored food by University of Benin community, in Benin City, Nigeria

The aim of the study is to determine the impact of Lassa fever on the consumption of processed snacks and food storage practices in University of Benin campuses. They found that the that majority discard their snacks when contaminated while some remove the contaminated portions and consume remaining part which could be a major health risk.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

This resource describes the main challenges of the implementation of a trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, it reports the aspects of the community’s communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved.

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'He is now like a brother, I can even give him some blood': Relational ethics and material exchanges in a malaria vaccine 'trial community' in The Gambia

This paper explores social relations within the ‘trial community’ (staff and volunteers) of a Malaria Vaccine Trial (MVT), implemented by the Medical Research Council (MRC) in The Gambia between 2001 and 2004. It situates ethical concerns with medical research within the everyday life of scientific fieldwork. Based upon discussions with volunteers and staff, it looks at processes of mediation between scientific project and study population, between formal ethics, local ethical debates, and everyday practice.

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