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Organizing the donation of convalescent plasma for a therapeutic clinical trial on Ebola Virus Disease: The experience in Guinea

This resource reports on the successful organization of donor mobilization and plasma collection as part of the Ebola-Tx clinical trial from November 2014 to July 2015 in Conakry, Guinea, the challenges they faced, and efforts made to address these.

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Social consequences of Ebola containment measures in Liberia

This study of quarantine during the Ebola epidemic in Liberia also shows that state-enforced quarantine, with a mandatory prohibition of movement, raised condemnation, strengthened stigmatization and created serious socio-economic distress.

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Burials in times of Ebola: Do's and don'ts - issues of acceptability

This short guide was elaborated by the authors at the beginning of the Ebola Virus disease outbreak in May 2014 in Gueckedou base on a fieldwork in the area. It compiles the wishes collected from villages where people died from Ebola virus diseases.

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Improving burial practices and cemetery management during an Ebola virus disease epidemic — Sierra Leone, 2014

This piece is a summary of an assessment conducted in Sierra Leone on the acceptability of safe, nontraditional burial practices and cemetery management during the Ebola Outbreak. Both measures aimed the control of the virus transmission. Some of the findings were: scarce burial teams, miscoordination among Ebola response bodies, lack of systematic procedures for testing and reporting results on dead bodies from Laboratories, inadequate cementerie space, no acceptance of safe burial practices by communities. These finding informed a standard operating procedure (SOP) for safe, dignified medical burials.

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Treating corpses like bundles of firewood. On the social production of indifference in the time of Ebola (Guinea)

The authors reflect on the impacts of the declaration of global emergency on the way dead bodies were treated during the Ebola virus disease epidemic in Guinea: focusing on problems related to anonymous graves and the impossibility of organizing burial ceremonies.

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Community-centered responses to Ebola in urban Liberia: The view from below

The article presents information on community-based epidemic control priorities and identifies innovative local strategies for containing EVD in Liberia. The text also offers some suggestions from participants like the integration of families in the surveillance system and the declaration of National Memorial Day among others.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

This resource describes the main challenges of the implementation of a trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, it reports the aspects of the community’s communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved.

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'He is now like a brother, I can even give him some blood': Relational ethics and material exchanges in a malaria vaccine 'trial community' in The Gambia

This paper explores social relations within the ‘trial community’ (staff and volunteers) of a Malaria Vaccine Trial (MVT), implemented by the Medical Research Council (MRC) in The Gambia between 2001 and 2004. It situates ethical concerns with medical research within the everyday life of scientific fieldwork. Based upon discussions with volunteers and staff, it looks at processes of mediation between scientific project and study population, between formal ethics, local ethical debates, and everyday practice.

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EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country

This article describes the experiences of the EBOVAC-Salone research team in setting up and implementing the trial, and provides recommendations for research teams aiming to conduct clinical trials in future outbreak situations.

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When experiments travel: Clinical trials and the global search for human subjects

This book aims to challenge conventional understandings of the ethics and politics of transnational science and change the way we think about global medicine and the new infrastructures of our lives. It explores the clinical trials industry through both an economic and cultural lens to examine the ways commercial medical science is currently being integrated into local health systems.

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