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Lassa fever in post-conflict Sierra Leone

This resource presents observations of case fatality rates of Lassa fever in Sierra Leone after the civil war and compared to studies completed prior to the conflict. Peak presentation of Lassa fever cases occurs in the dry season, which is consistent with previous studies. This paper's studies also confirmed reports conducted prior to the civil war that indicate that infants, children, young adults, and pregnant women are disproportionately impacted by Lassa fever.

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WHO: Lassa fever research and development (R&D) roadmap

This resource provides a framework for identifying the vision, underpinning strategic goals, and prioritizing areas and activities for accelerating the collaborative development of medical countermeasures.

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Power, fairness and trust : understanding and engaging with vaccine trial participants and communities in the setting up the EVOVAC-Salone vaccine trial in Sierra Leone

In this article the authors discuss the implementation of an Ebola vaccine trial in Kambia district in Sierra Leone during and after the epidemic. They analyze the role of social science research for the development of community engagement strategies. The authors give special attention to the analysis of rumours as source of information and explanation about resistance rooted in a much deeper sociopolitical context.

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Lassa fever: The politics of an emerging disease and the scope for One Health

As a rodent borne virus, Lassa fever is of particular interest from a One Health perspective. The interplay between security, public health and One Health approaches are explored through ethnographic and interview based research in Kenema, Sierra Leone, a long-term treatment and research hub. ‘Biodefence dollars’ have provided the majority of recent funding in Sierra Leone and have created opportunities for both local and international actors to address a neglected disease.

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Understanding the cryptic nature of Lassa fever in West Africa

In this article the authors give an overview of the current knowledge on Lassa fever (ecology, epidemiology and distribution) and the importance of future socio-ecological changes in the increase of Lassa fever burden.

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Using modelling to disentangle the relative contributions of zoonotic and anthroponotic transmission: The case of Lassa fever

The authors present the results of a modelling approach, using published data from outbreak and patients to Kenema governmental Hospital in Sierra Leone. They estimate the likely contribution to human to human transmission. They shed light on the need to better assess the human to human transmission.

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U.S. Centre for Disease Control (CDC): Lassa fever

Further information from the U.S. CDC in both English and French about the transmission, prevention, diagnosis and treatment of Lassa fever.

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U.S Centre for Disease Control (CDC): Ebola hemorrhagic fever information packet

This resource provides a fact sheet for Ebola as well as a case count and location list for April 9th, 2010.

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Safe intensive-care management of a severe case of Lassa fever with simple barrier nursing techniques

This resource describes the case-management of Lassa fever in a specific patient and the difficulties encountered in repatriating her for diagnosis and management, which is unavailable in Sierra Leone, are described.The experience with this case has implications for the medical care and safe handling of Lassa fever in both endemic and nonendemic areas.

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The use of Lassa fever convalescent plasma in Nigeria

This resource describes the use of Lassa fever convalescent plasma amongst patients at hospitals in Jos and Vom, Nigeria as a potential therapy. 

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