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Displaying 1 - 10 of 23 results.

Evaluation of rodent control to fight Lassa fever based on field data and mathematical modelling

This resource aims to to assess the efficacy of rodent control by performing a 4-year field experiment in rural Upper Guinea, and developing a mathematical model to simulate different control strategies (annual density control, continuous density control, and rodent vaccination).

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Evidence that rodent control strategies ought to be improved to enhance food security and reduce the risk of rodent-borne illnesses within subsistence farming villages in the plague/endemic West Nile region, Uganda

This resource presents a survey of 37 households from 17 subsistence farming villages within the West Nile region of Uganda. This revealed that rodents cause both pre- and post-harvest damage to crops. Evidence of rodent access to stored foods was reported in conjunction with each of the reported storage practices, and the paper suggests that current efforts are inadequate for effectively reducing rodent abundance in homes.

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Case-control study of Mastomys natalensis and humans in Lassa virus-infected households in Sierra Leone

This resource studied Lassa virus infection and antibodies in households where Lassa fever cases occurred and compared these to those in the nearest neighbour houses and "far" houses located across the village. It reports on rodent infection and human anti-body prevalence. 

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The bioeconomics of controlling an African rodent pest species

This resource presents an ecological population model as a basis for an economic analyses of controlling an African pest rodent, the multimammate rate, which causes major damage in maize production. This study sues data from the village level in Tanzania, and the model incorporates density-dependent and density-independent factors.

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Acute sensorineural deafness in Lassa fever

This resource describes a prospective audiometric evaluation of 69 hospitalized febrile patients in Sierra Leone, West Africa, that revealed a sensorineural hearing deficit (SNHD) in 14 (29%) of 49 confirmed cases of Lassa fever and in 0 of 20 febrile controls. This study found that lassa fever is associated with an incidence of SNHD, which considerably exceeds that previously reported with any other postnatally acquired infection.

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Therapy management: Concept, reality, process

This resource described the two concepts of "therapy management" (diagnosis, selection, and evaluation of treatment, as well as support of the sufferer) and "therapy management group" (the set of individuals who take charge of therapy management with or on behalf of the sufferer) as developed in medical anthropology research in Central Africa. It explores their historical development, current use by researchers, and potential future uses in contextually sensitive analyses. 

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Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

This resource summarises clinical findings of hearing loss in Lassa fever (LF) patients highlighting the association between Lassa virus infection and sudden-onset sensorineural hearing loss (SNHL), as well as the potential mechanism(s) for LF-induced SNHL. The study highlights that further research is necessary to identify the mechanism and the epidemiology of LF-induced SNHL.

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Sensorineural hearing loss in Lassa fever: Two case reports

This resource reports on two female patients aged 19 and 43 years old with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction. Both patients developed severe sensorineural hearing loss at acute phases of the infections.

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Epidemic preparedness and management: A guide on Lassa fever outbreak preparedness plan

This resource discusses the principles of epidemic management using an emergency operating center model, reviews the epidemiology of Lassa fever in Nigeria, and provides guidance on what is expected to be done in preparing for an epidemic of the disease at health facilities and local and state government levels in line with the Integrated Disease Surveillance and Response strategy.

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Knowledge and application of infectious diseases control measures among primary care workers in Nigeria: The Lassa fever example

This resource investigates the knowledge and practice of Lassa fever control among primary care health workers. The study was a cross-sectional survey of health workers in 34 primary care centres in Esan West and Esan Central Local Government Areas.

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