Resources

Lassa Fever: a rodent-human interaction

This resource examines the sites of interactions between humans and the multimammate mouse, Mastomys natalensis. It presents findings such as new arenaviruses in other African rodents and in snakes, that  argue preferably toward the host-switching concept. The recent emergence in Sierra Leone, the absence of virus positive Mastomys between the two endemic zones and poor virus diversity in the Mano River area also point in the direction of a unique import of Lassa virus from Nigeria to Sierra Leone during the 19th century. This resource also discusses the hypothesis of human displacements through the Atlantic slave trade and its abolition in 1807.

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Acute sensorineural deafness in Lassa fever

This resource describes a prospective audiometric evaluation of 69 hospitalized febrile patients in Sierra Leone, West Africa, that revealed a sensorineural hearing deficit (SNHD) in 14 (29%) of 49 confirmed cases of Lassa fever and in 0 of 20 febrile controls. This study found that lassa fever is associated with an incidence of SNHD, which considerably exceeds that previously reported with any other postnatally acquired infection.

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Healthcare providers on the frontlines: A qualitative investigation of the social and emotional impact of delivering health services during Sierra Leone’s Ebola epidemic

This paper describes the stigma experienced by health care workers during the Ebola epidemic in Sierra Leone, and recommends psychological support mechanisms for medical staff working in epidemic contexts.

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Lassa fever: Epidemiology, clinical features, and social consequences

This resource describes the epidemiology of Lassa fever and its vector, as well as the clinical course and management of the disease. It then reports on current treatment efforts, surveillance and disease control before presenting community perspectives through a knowledge, attitude and practice survey and a qualitative study.  

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