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Acute sensorineural deafness in Lassa fever

This resource describes a prospective audiometric evaluation of 69 hospitalized febrile patients in Sierra Leone, West Africa, that revealed a sensorineural hearing deficit (SNHD) in 14 (29%) of 49 confirmed cases of Lassa fever and in 0 of 20 febrile controls. This study found that lassa fever is associated with an incidence of SNHD, which considerably exceeds that previously reported with any other postnatally acquired infection.

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Therapy management: Concept, reality, process

This resource described the two concepts of "therapy management" (diagnosis, selection, and evaluation of treatment, as well as support of the sufferer) and "therapy management group" (the set of individuals who take charge of therapy management with or on behalf of the sufferer) as developed in medical anthropology research in Central Africa. It explores their historical development, current use by researchers, and potential future uses in contextually sensitive analyses. 

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Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

This resource summarises clinical findings of hearing loss in Lassa fever (LF) patients highlighting the association between Lassa virus infection and sudden-onset sensorineural hearing loss (SNHL), as well as the potential mechanism(s) for LF-induced SNHL. The study highlights that further research is necessary to identify the mechanism and the epidemiology of LF-induced SNHL.

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Sensorineural hearing loss in Lassa fever: Two case reports

This resource reports on two female patients aged 19 and 43 years old with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction. Both patients developed severe sensorineural hearing loss at acute phases of the infections.

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Epidemic preparedness and management: A guide on Lassa fever outbreak preparedness plan

This resource discusses the principles of epidemic management using an emergency operating center model, reviews the epidemiology of Lassa fever in Nigeria, and provides guidance on what is expected to be done in preparing for an epidemic of the disease at health facilities and local and state government levels in line with the Integrated Disease Surveillance and Response strategy.

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Knowledge and application of infectious diseases control measures among primary care workers in Nigeria: The Lassa fever example

This resource investigates the knowledge and practice of Lassa fever control among primary care health workers. The study was a cross-sectional survey of health workers in 34 primary care centres in Esan West and Esan Central Local Government Areas.

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Epidemics and related cultural factors for Ebola hemorrhagic fever in Gabon

This resource collected information about Ebola hemorrhagic fever (EHF) epidemics from the Gabon Ministry of Health, district hospitals and other facilities and conducted in-depth interviews with 20 villagers and 2 traditional healers in the village where the third epidemic occurred. This study suggests that cultural factors might be very crucial to EHF outbreaks in developing countries. Quick intervention with health education is needed to disseminate appropriate knowledge and persuade people that traditional practices could carry a high risk of infection

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Review of cases of nosocomial Lassa fever in Nigeria: The high price of poor medical practice

This resource reviewed medical records in hospitals and clinics in rural and urban areas of Imo State, Nigeria, and reports on its investigation into two hospital outbreaks. In this study, patients with presumed and laboratory confirmed Lassa fever were identified and contracts traced. Hospital staff, patients, and local residents were questioned, records were carefully reviewed, and serum samples were taken. Serum samples were assayed for antibody specific to Lassa virus, and isolates of Lassa virus were obtained.

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A hospital epidemic of Lassa fever in Zorzor, Liberia

This resource describes the epidemic of Lassa fever at a missionary hospital in Zorzor, Liberia, and clinical features and diagnostics. It then goes on to examine both the index case and the subsequent search for further cases. 

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Lassa Virus Hemorrhagic Fever in Benin in 2014 in an Ebola Context: An Epidemic Revealing the Weakness of the Health System

This resource aims to understand the social conditions of the outbreak and evolution of the Lassa haemorrhagic fever epidemic in Benin, 2014, and the technical, political and institutional processes of its management by the state and international alert network and health response. It reports on the results of a qualitative survey conducted at several sites: at the Ministry of Health in Cotonou, in the health services (including the Saint-Jean de Dieu Hospital in Tanguiéta in the north of the country), and in the families of the geographical area of ​​the epidemic.

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