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Displaying 11 - 18 of 18 results.

Engaging ‘communities’: Anthropological insights from the West African Ebola epidemic

This resource reflects on the nature of community engagement during the Ebola epidemic and demonstrates a disjuncture between local realities and what is being imagined in post-Ebola reports about the lessons that need to be learned for the future. It argues that to achieve stated aims of building trust and strengthening outbreak response and health systems, public health institutions need to reorientate their conceptualization of ‘the community’ and develop ways of working which take complex social and political relationships into account.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

This resource describes the main challenges of the implementation of a trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, it reports the aspects of the community’s communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved.

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'He is now like a brother, I can even give him some blood': Relational ethics and material exchanges in a malaria vaccine 'trial community' in The Gambia

This paper explores social relations within the ‘trial community’ (staff and volunteers) of a Malaria Vaccine Trial (MVT), implemented by the Medical Research Council (MRC) in The Gambia between 2001 and 2004. It situates ethical concerns with medical research within the everyday life of scientific fieldwork. Based upon discussions with volunteers and staff, it looks at processes of mediation between scientific project and study population, between formal ethics, local ethical debates, and everyday practice.

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EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country

This article describes the experiences of the EBOVAC-Salone research team in setting up and implementing the trial, and provides recommendations for research teams aiming to conduct clinical trials in future outbreak situations.

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When experiments travel: Clinical trials and the global search for human subjects

This book aims to challenge conventional understandings of the ethics and politics of transnational science and change the way we think about global medicine and the new infrastructures of our lives. It explores the clinical trials industry through both an economic and cultural lens to examine the ways commercial medical science is currently being integrated into local health systems.

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WHO: Efficacy trials of Lassa therapeutics: endpoints, trial design, site selection

This resource is a final report of a WHO workshop regarding efficacy trials of Lassa therapeutics. 

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WHO: Target product profile for Lassa virus vaccine

This resource is an outline of the WHO target product profile development  for Lassa, as well as a generic description of WHO's Vaccine Pre-qualification process.

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Land tenure in Sierra Leone: the law, dualism, and the making of a land policy

This book gives a brief account of the background to the dual land tenure system in force in Sierra Leone and explains the reasons why the dualism derived from the different colonial experience of the former Colony and Protectorate of Sierra Leone still persists. It also gives an account of the main features of the English derived land law in the Western Area and of the forms of land holding in the Provinces which are governed predominately by customary law.

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