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Evaluation of rodent control to fight Lassa fever based on field data and mathematical modelling

This resource aims to to assess the efficacy of rodent control by performing a 4-year field experiment in rural Upper Guinea, and developing a mathematical model to simulate different control strategies (annual density control, continuous density control, and rodent vaccination).

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Lassa fever. Epidemiological aspects of the 1970 epidemic

This resource describes the contact tracing of patients during a hospital centred outbreak of Lassa fever in early 1970 in Jos, Nigeria. 

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Nigeria Centre for Disease Control (NCDC): Viral haemorrhagic fever factsheet

This factsheet provides information on viral haemorrhagic fevers from the Nigeria Centre for Disease Control.

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Lassa Fever: a rodent-human interaction

This resource examines the sites of interactions between humans and the multimammate mouse, Mastomys natalensis. It presents findings such as new arenaviruses in other African rodents and in snakes, that  argue preferably toward the host-switching concept. The recent emergence in Sierra Leone, the absence of virus positive Mastomys between the two endemic zones and poor virus diversity in the Mano River area also point in the direction of a unique import of Lassa virus from Nigeria to Sierra Leone during the 19th century. This resource also discusses the hypothesis of human displacements through the Atlantic slave trade and its abolition in 1807.

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Diversity and dynamics in a community of small mammals in coastal Guinea, West Africa

This resource investigated three villages in high endemic zones of Lassa fever in Guinea and presents the biodeiversity of the small mammal community identified through standardized trapping in houses, cultivations and forest.

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Nigeria Centre for Disease Control (NCDC): Standard operating procedures for Lassa fever case management

This resource describes the standard operating procedures for Lassa fever case management as outlined by the Nigeria Centre for Disease Control.

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Sensorineural hearing loss in Lassa fever: Two case reports

This resource reports on two female patients aged 19 and 43 years old with clinical features suggestive of Lassa fever and confirmed by immunoserological/Lassa-virus-specific reverse transcriptase polymerase chain reaction. Both patients developed severe sensorineural hearing loss at acute phases of the infections.

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Epidemic preparedness and management: A guide on Lassa fever outbreak preparedness plan

This resource discusses the principles of epidemic management using an emergency operating center model, reviews the epidemiology of Lassa fever in Nigeria, and provides guidance on what is expected to be done in preparing for an epidemic of the disease at health facilities and local and state government levels in line with the Integrated Disease Surveillance and Response strategy.

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Knowledge and application of infectious diseases control measures among primary care workers in Nigeria: The Lassa fever example

This resource investigates the knowledge and practice of Lassa fever control among primary care health workers. The study was a cross-sectional survey of health workers in 34 primary care centres in Esan West and Esan Central Local Government Areas.

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Review of cases of nosocomial Lassa fever in Nigeria: The high price of poor medical practice

This resource reviewed medical records in hospitals and clinics in rural and urban areas of Imo State, Nigeria, and reports on its investigation into two hospital outbreaks. In this study, patients with presumed and laboratory confirmed Lassa fever were identified and contracts traced. Hospital staff, patients, and local residents were questioned, records were carefully reviewed, and serum samples were taken. Serum samples were assayed for antibody specific to Lassa virus, and isolates of Lassa virus were obtained.

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