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Engaging ‘communities’: Anthropological insights from the West African Ebola epidemic

This resource reflects on the nature of community engagement during the Ebola epidemic and demonstrates a disjuncture between local realities and what is being imagined in post-Ebola reports about the lessons that need to be learned for the future. It argues that to achieve stated aims of building trust and strengthening outbreak response and health systems, public health institutions need to reorientate their conceptualization of ‘the community’ and develop ways of working which take complex social and political relationships into account.

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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa

This resource describes the main challenges of the implementation of a trial in the Ebola treatment center of Guéckédou. Following the principles of the Good Clinical Research Practices, it reports the aspects of the community’s communication and engagement, ethical conduct, trial protocol compliance, informed consent of participants, ongoing benefit/risk assessment, record keeping, confidentiality of patients and study data, and roles and responsibilities of the actors involved.

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U.S. Centre for Disease Control (CDC): Lassa fever

Further information from the U.S. CDC in both English and French about the transmission, prevention, diagnosis and treatment of Lassa fever.

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U.S Centre for Disease Control (CDC): Ebola hemorrhagic fever information packet

This resource provides a fact sheet for Ebola as well as a case count and location list for April 9th, 2010.

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Safe intensive-care management of a severe case of Lassa fever with simple barrier nursing techniques

This resource describes the case-management of Lassa fever in a specific patient and the difficulties encountered in repatriating her for diagnosis and management, which is unavailable in Sierra Leone, are described.The experience with this case has implications for the medical care and safe handling of Lassa fever in both endemic and nonendemic areas.

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The use of Lassa fever convalescent plasma in Nigeria

This resource describes the use of Lassa fever convalescent plasma amongst patients at hospitals in Jos and Vom, Nigeria as a potential therapy. 

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'He is now like a brother, I can even give him some blood': Relational ethics and material exchanges in a malaria vaccine 'trial community' in The Gambia

This paper explores social relations within the ‘trial community’ (staff and volunteers) of a Malaria Vaccine Trial (MVT), implemented by the Medical Research Council (MRC) in The Gambia between 2001 and 2004. It situates ethical concerns with medical research within the everyday life of scientific fieldwork. Based upon discussions with volunteers and staff, it looks at processes of mediation between scientific project and study population, between formal ethics, local ethical debates, and everyday practice.

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Popular concerns about medical research projects in sub-Saharan Africa – a critical voice in debates about medical research ethics

This resource aims to move beyond the dismissal of stories about blood-stealing and trade in body parts as ‘mere’ rumour, based on erroneous belief or traditional superstition, and to instead appreciate them as modern commentaries on social relations that involve, and extend far beyond, scientific medical research.

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'Transport to where?': Reflections on the problem of value and time à propos an awkward practice in medical research

This resource examines the gap between the bioethics aversion to value transfers in clinical trials, and research participants' and researchers' expectations of these. It focuses upon so-called 'transport reimbursement' (TR): monetary payments to participants that are framed as mere refund of transport expenses, but which are of considerable value to recipients.

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EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country

This article describes the experiences of the EBOVAC-Salone research team in setting up and implementing the trial, and provides recommendations for research teams aiming to conduct clinical trials in future outbreak situations.

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